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Glossary:
Deep Salvage
After all drugs have failed
Definitely Does
The physician see RT as a prime determinant when selecting drug therapy based on RT results
Definitely Does Not
The physician does not see RT as a prime determinant when selecting drug therapy based on RT results
Do Not Know
Has not encountered or is not familiar with the question or situation
First Failure
Patient fails to respond to one or more of the initial antiretroviral drugs prescribed
HIV-1 Drug Resistance Test (RT)
"Resistance testing generally involves determining the genotype or phenotype of a virus. The genotype refers to the sequence of nucleotides in the viral genome that determine the genes of the virus. Genotypic assays are assays that determine the nucleotide sequence of specific genes, or parts of genes. ...Phenotypic assays for drug susceptibility determine the amount of drug needed to inhibit viral growth in tissue culture." Daniel R. Kuritzkes, MD Associate Professor of Medicine and Microbiology, University of Colorado Health Sciences Center, Co=Director, Colorado AIDS Clinical Trials Unit
Minor Issue
The physician see RT as a something to consider, but it is not a determinant when selecting drug therapy based on RT results
Not Discussed
Representative does not discuss the subject with the physician
Not Seen RT Used
Representative has not directly observed or discussed RT with physicians
Salvage Therapy
After the patient fails to respond to three or four drug regimens
S. R. Ware Associates
SRWA is a consultant group focused on pre- and post-launch pharmaceutical, biotechnology, or laboratory products that require approval from Medicaid, Medicare or other entities.
Therapeutic Drug Monitoring (TDM)
"Therapeutic Drug Monitoring (TDM) measures or confirms (in the context of HIV drug therapy) a plasma drug concentration which is above or below the therapeutic range" Author Unknown
Treatment Naïve
Never experienced antiretroviral drugs
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